The U.S. vape market size is expected to reach USD 40.26 billion by 2028. It is projected to register a CAGR of 27.4% from 2021 to 2028. Various factors, such as the rapid growth of vape shops in the U.S. and the increasing popularity of e-cigarettes among the youth population, is expected to drive market growth over the forecast period. E-cigarettes and vape mods are being increasingly used by users as a substitute for smoking traditional cigarettes.