A new study conducted by researchers from Imperial Tobacco in the United Kingdom is consistent with the results of previous studies, showing that acute exposure of lung tissue to e-cigarette vapor has less effect on genetic performance than cigarette smoke. The study was published in the journal Toxicological Research & Application with the title: "Compared with cigarette smoke, 3D human bronchial tissue’s acute e-vapor product overall aerosol exposure resulted in minimal cell and transcription Level changes.

In order to understand the effects of steam and smoke exposure on health, the study compared the cells in the three-dimensional human bronchial model under strict laboratory conditions to compare the sub-cytotoxicity of nicotine-containing e-cigarette aerosols, combustible cigarette smoke and ordinary fresh air Exposed. Then, the researchers evaluated the expression of various genes related to the disease after the cell recovery period of 4 hours and 48 hours. They found that exposure to cigarette smoke caused significant changes in gene expression, including changes in oxidative stress and inflammatory markers.

On the other hand, the e-cigarette vapor produced only a minimal response, similar to what is observed when cells are exposed to fresh air. Dr. Liam Sims, the chief toxicologist at Imperial College London, said: “Take the 3R4F reference cigarette as an example. Although there is no change in the cells after 4 hours of exposure to cigarette smoke, after 48 hours, the cells are Genes related to the cell death pathway were activated. In contrast, those cells exposed to the e-cigarette aerosol showed a slight increase in the NF-KappaB (nuclear transcription factor) signaling pathway after four hours of exposure; however, at 48 After hours, no pathway was activated.” These data provide evidence that the experimentally cultured lung cells are significantly less damaged after acute exposure to electronic cigarette (EVP) aerosols than the same dose of nicotine-based cigarette smoke.

Dr. Grant O’Connor, head of the Department of Tobacco Harm Reduction Science at Imperial College London, said: “This study and other studies with the same conclusions should give attention and consideration when formulating policies. These data show that it is compatible with continued smoking of combustible cigarettes. In comparison, next-generation products (NGPs) such as e-cigarettes have considerable potential for harm reduction.

Prev : Ukrainian e-cigarette

Next : Washington Vape

Email:sales@mlifevapor.com

WhatsApp:+86 13871529372

Email:sales@mlifevapor.com

WhatsApp:+86 13871529372

Tel：+86 13871529372

Add：6 / F, block B, building 2, Fuyong Tongtai times center, Bao'an District, Shenzhen

Language：简体中文 | >

Tel：+86 13871529372

Add：6 / F, block B, building 2, Fuyong Tongtai times center, Bao'an District, Shenzhen Website