Recently, a research report published in the authoritative journal "Nicotine & Tobacco Research" (Nicotine & Tobacco Research) pointed out that when the nicotine content is appropriate, e-cigarettes have a significant effect on smoking cessation and are superior to other methods, even if smokers do not have strong Willingness to quit smoking, smoking cessation rate can reach 11% after switching to e-cigarettes.

The study was jointly completed by researchers from the Pennsylvania State University School of Medicine and Virginia Commonwealth University, and was supported by the National Institute of Drug Abuse of the National Institutes of Health (NIH) and the Tobacco Center of the U.S. Food and Drug Administration (FDA).

The study selected a total of 520 cigarette smokers as the subjects of clinical trial observation, according to the use of nicotine-free e-cigarettes, the use of e-cigarettes with 8mg/ml nicotine content, the use of e-cigarettes with 36mg/ml nicotine content, and the use of nicotine substitutes such as nicotine patches. These four situations are randomly grouped.

The test results show that the smoking cessation rate of smokers in the 36mg/ml group was 11%, the smoking cessation rate of smokers in the 8mg/ml group was 5%, the smoking cessation rate of the nicotine substitute group was 3%, and the smoking cessation rate of users without nicotine e-cigarettes The lowest, only 1%.

In response to this data, Penn State University Cancer Institute researcher Jessica Yingst (Jessica Yingst) said, "The effect of e-cigarettes in smoking cessation is very obvious, but the smoking cessation rate of the 8mg/ml group is not improved compared with the nicotine replacement group. This shows that if e-cigarettes can provide similar nicotine content to cigarettes, the effect of smoking cessation will be better. On the contrary, the reduction of nicotine content will also reduce the smoking cessation rate."

In addition to the higher smoking cessation rate, smokers in the 36mg/ml group had significantly higher non-smoking days than the other three groups during the 6-month trial.

The lead author of the paper, Jonathan Foulds, a professor of public health at the Pennsylvania State University School of Medicine, said: “Because this clinical trial only recommends that subjects reduce smoking and does not require smoking cessation, the overall smoking cessation rate is low. However, as time goes by, the number of smokers who have switched to e-cigarettes is gradually increasing, while smokers who use nicotine-free e-cigarettes or cigarette substitutes have not shown this trend."

The researchers also pointed out that smokers who switched to e-cigarettes during the trial did not experience adverse reactions. This is also similar to the research conclusions of many international authorities.

For example, the Cochrane Collaboration, an internationally authoritative academic organization for evidence-based medicine, also highlighted in a review report published this year that after referring to multiple experiments, no evidence that electronic cigarettes are harmful to humans has been found. .

Jonathan Folz pointed out in the report that although e-cigarettes are not completely harmless, the results of this experiment show that e-cigarettes have a very significant smoking cessation effect. The most important point is the nicotine content. The nicotine content is similar to that of cigarettes, and the effect of smoking cessation is the best.

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